Phospho-h2ax ser139
WebFeb 2, 2024 · (D, E) IHC staining of phospho‐BRCA1 (Ser1423) and phospho‐H2AX (Ser139) on MM samples (N ≧ 7). Compared with the wild‐type, the Brca1 Mut group revealed similar fractions of EM and no malignancy, but a higher fraction of SM, as well as a lower proportion of BM (Figure 1D ), indicating the promotion of epithelial–mesenchymal ... WebProduct Specific Information. Description: The CR55T33 monoclonal antibody recognizes phosphorylated serine 139 of human and mouse H2AX. H2AX is a member of the H2A …
Phospho-h2ax ser139
Did you know?
WebApr 14, 2024 · Abstract. Background: HER3, a member of the ERBB family of receptor tyrosine kinases that activates multiple oncogenic signaling pathways, is overexpressed in 50-70% of breast cancers (BC). HER3 mRNA expression is highest in luminal (ER+) breast tumors. Approximately 30% of ER+ breast tumors are de novo resistant to tamoxifen. … WebDescription Histone H2AX is a variant of the nucleosome core histone H2A and is phosphorylated at Ser139 in response to DNA damage. Histone H2AX phosphorylation is considered a specific reporter of double-strand DNA breaks. The protein is also referred to as γH2AX when phosphorylated at Ser139.
WebUse Anti-phospho-Histone H2A.X (Ser139) Antibody, clone JBW301, FITC conjugate (mouse monoclonal antibody) validated in FC, ICC to detect phospho-Histone H2A.X (Ser139) also known as H2AXS139P, H2AX h More>> MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. SDS CoA References WebPhosphorylated H2A.X promotes DNA repair and maintains genomic stability. The 2F3 monoclonal antibody reacts with phosphorylated human H2A.X (Ser139) and has been shown to be useful for Western blotting, immunofluorescence and flow cytometry. Product Details Technical data sheet Product Details Verified Reactivity Human, Mouse Antibody …
WebNov 15, 2024 · RayBio® Phospho-H2AX (S139) and Total H2AX ELISA kit is a very rapid, convenient and sensitive assay kit that can monitor the activation or function of important … WebPhosphorylated H2A.X promotes DNA repair and maintains genomic stability. The 2F3 monoclonal antibody reacts with phosphorylated human H2A.X (Ser139) and has been shown to be useful for Western blotting, immunofluorescence and flow cytometry. Product Details Technical data sheet Product Details Isotype Control FITC Mouse IgG1, κ Isotype …
WebIntracellular staining protocol for Anti-H2A.X-Phosphorylated (Ser139) Antibody for Flow Cytometry. 1. Prepare 70% absolute ethanol. Chill solution by storing at -20°C. 2. Prepare cells of interest. 3. Wash 1X with PBS, centrifuge at 350g for 5 min. 4.
WebDescription. Histone H2AX is a variant of the nucleosome core histone H2A and is phosphorylated at Ser139 in response to DNA damage. Histone H2AX phosphorylation is considered a specific reporter of double-strand DNA breaks. The protein is also referred to as γH2AX when phosphorylated at Ser139. H2AX phosphorylation is especially strong in ... sonata delray beach flWebThis Histone H2AX phospho Ser139 antibody was raised against a peptide including phospho-serine 139 of histone H2AX. Buffer 10 mM sodium phosphate pH 7.5, 150 mM … small day sailboats for saleWebBecause phosphorylation of H2AX at Ser 139 (γ-H2AX) is abundant, fast, and correlates well with each DSB, it is the most sensitive marker that can be used to examine the DNA … sonata fitness bandsmall days songWebThe AlphaLISA SureFire Ultra Phospho-Histone H2A.X (Ser139) assay kit is an immunoassay for quantitative detection of phosphorylated Histone H2A.X in cellular lysates. We are now two standalone organizations Life Sciences & Diagnostics and Analytical & Enterprise Solutions small days and nightsWebThis Anti-phospho Histone H2A.X (Ser139) antibody, clone JBW301, Alexa Fluor ® 488 Conjugate is validated for use in ICC for the detection of phospho Histone H2A.X (Ser139). Quality Evaluated by Immunocytochemistry in untreated (negative control) and Staurosporin treated HeLa cells. small daypacks for travel denver coWebAtrazine, a pre-emergent herbicide in the chloro-s-triazine family, has been widely used in crop lands and often detected in agriculture watersheds, which is considered as a … small day planners for women