WebHeterochromatin "Heterochromatin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity. MeSH information ... WebSep 15, 2024 · Mechanistically, LIN28 maintains a peri-nucleolar heterochromatin-residing complex to repress 2C activator Dux via association with NCL and TRIM28. Meanwhile, it promotes liquid-liquid phase separation (LLPS) of nucleolar proteins FBL and NCL to support nucleolar function through its RNA binding domains and intrinsic disordered …

IRIF formation of NPM1. A, HeLa cells were untreated (−) or …

WebSep 24, 2024 · To understand how this bidirectional transition takes place, we performed single-cell RNA sequencing on isolated 2CLCs that underwent 2C-like state exit and re-entry, and revealed a step-by-step... WebOct 7, 2024 · peri-nucleolar heterochromatin Introduction Mouse embryonic stem cells (mESCs) in culture exhibit cell-to-cell heterogeneity, with about 1% of them spontaneously … earing credit card

Ribosomal proteins regulate 2-cell-stage transcriptome in mouse ...

WebTaken together, these data demonstrated that reduced peri-nucleolar heterochromatin around the Dux locus at the G1/early S phase might facilitate 2C gene expression (Figure … WebTitle. rRNA Biogenesis Regulates Mouse 2C-like State by 3D Structure Reorganization of Peri-Nucleolar Heterochromatin. Organism. Mus musculus. Experiment type. Expression profiling by high throughput sequencing. Genome binding/occupancy profiling by high throughput sequencing. Other. Summary. WebOct 26, 2024 · ZGA usually occurs in two subsequent steps: a minor ZGA which predominantly takes place in the paternal pronucleus and a more substantial major ZGA which occurs in a 2-cell mouse embryo or 8-cell human embryo ( Eckersley-Maslin et al., 2024 ). Minor ZGA is a prerequisite of major ZGA. earing defect